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Administration of codeine could possibly be accompanied by histamine release and will be made use of with warning in atopic young children.

The effect of promethazine and/or codeine on later growth and improvement with the new child is not known.

Codeine: A analyze in rats and rabbits described no teratogenic effect of codeine administered in the course of the period of organogenesis in doses starting from five to 120 mg/kg. Inside the rat, doses at the 120mg/ kg degree, during the toxic selection for the adult animal, have been related to an increase in embryo resorption at time of implantation.

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Sphincter of Oddi Spasm. The sphincter of Oddi is really a muscular valve in The body that controls the movement of bile and digestive juices with the pancreas to the smaller intestine. When this valve spasms, it could sense like getting a tight muscle mass cramp, leading to discomfort and blocking the movement of such juices, which can result in discomfort and digestive issues.

與其它鴉片類藥物一樣，可待因的其中一個潛在的嚴重不良反應是壓抑呼吸，通常與服用過量有關，可引致死亡。

Codeine sulfate is usually a type of this drug that is often utilised. It is on the market in tablet type Label and indicated to the relief of gentle to moderately critical pain, where by using an opioid analgesic is suitable Label.

常見之不良反應有：瘙癢、噁心、嘔吐、昏睡、口乾、瞳孔縮小、姿態性低血壓（orthostatic hypotension）、小便不暢、便秘。

We have been happy to never compromise on our main target: to put affected person perfectly-being above all else. We've been happy to generate the public’s trust as tablet-ers of Culture. We only dispense Wellbeing copyright-accepted prescription drugs and keep ourselves to the very best levels of Skilled carry out.

This info shouldn't be interpreted without the enable of the Health care provider. If you believe read more you will be encountering an interaction, Speak to a Health care company straight away. The absence of the conversation does not necessarily imply no interactions exist.

NMS is a serious situation that can lead to Loss of life. Prevent taking promethazine/phenylephrine/codeine and call your healthcare supplier immediately When you have any of the subsequent signs and symptoms.

薬物乱用問題は直接摂取以外にもある。コデインを成分とする市販のせき止め薬から化学処理により強力な麻薬デソモルヒネを密造する方法であり、その方法がインターネット経由で広まり、ロシアなどの地域で乱用被害の増加が問題になっている[要出典]。